Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. Of or pertaining to mycolic acid

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

Back-formation from mycolic acid, in turn from Mycolata.

Examples

  • Parrish NM, Houston T, Jones PB, Townsend C, Dick JD (2001) In vitro activity of a novel antimycobacterial compound, N-octanesulfonylacetamide, and its effects on lipid and mycolic acid synthesis.

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  • Mycobacterium tuberculosis FAS-II condensing enzymes: their role in mycolic acid biosynthesis, acid-fastness, pathogenesis and in future drug development.

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  • As a result, the compositions of the outer membrane, consisting of arabinogalactan, mycolic acids, lipids, and pore-forming proteins (MspA), dominate the contribution in the observed vastly complicated SERS spectra.

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  • These unique profiles might reflect the presence of mycolic acid and other unique components that are found in cell envelope of Gram-negative bacteria in different growth phases exhibit discernibly different SERS spectral profiles

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  • Extracts of total fatty acid methyl esters (FAMEs) and mycolic acid methyl esters (MAMEs) from untreated and platensimycin treated cultures (5-60 µg/ml) were analysed by TLC-autoradiography.

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  • Structures of the major mycolic acids of M. tuberculosis and doi: 10.1371/journal. pone.0006306.g002

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  • Lawson EH, Groger RK, Woodruff A, et al. (2003) Requirement for kasB in Mycobacterium mycolic acid biosynthesis, cell wall impermeability and intracellular survival: implications for therapy.

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  • M. tuberculosis synthesised shorter mycolic acids with almost a complete loss of trans-cyclopropanation of oxygenated mycolic acids that resulted in increased susceptibility to lipophilic antibiotics

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  • We observed inhibition of both mycobacterial FAS-I and FAS-II in vitro in cell free assays and resultant inhibition of both fatty acid and mycolic acid biosynthesis in whole cells treated with the antibiotic.

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  • M. smegmatis strains to incorporate [14C] - acetate into fatty acids and mycolic acids was examined.

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