Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A structure of elongated multinucleate cells that contains some peripherally located myofibrils

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

From myo- +‎ tube

Examples

  • Staining of the myotube-like elongated B16-GFP cells with myogenic markers (MyoD and MF20) confirmed the fusion and incorporation of melanoma cells into myotubes.

    PLoS ONE Alerts: New Articles

  • B16-F10 cells display two distinctive features in response to co-culturing with myogenic cells: the absence of melanin production and the acquisition of a myotube-like morphology.

    PLoS ONE Alerts: New Articles

  • Events are repeated in a stepwise manner first leading to the formation of a bi/trinucleate precursor, followed by more such rounds of fusion, accompanied by growth at the ends of the myotube.

    PLoS ONE Alerts: New Articles

  • In the later phase of fusion, Rols and Loner appear to sustain fusion by interacting with and translocating Duf to the surface of the myotube

    PLoS ONE Alerts: New Articles

  • As has been suggested in the case of Rols, Loner too might serve to regulate Duf at the surface of the myotube through as yet unknown mechanisms.

    PLoS ONE Alerts: New Articles

  • That the functions of Duf cannot be attributed to particular motifs might be a strategy utilised to ensure that normal myotube development occurs in a robust manner and compromising the function of any of these motifs singly, does not drastically affect the overall process.

    PLoS ONE Alerts: New Articles

  • Arrow indicates Rols at the site of FCM-precursor/myotube contact (arrow in B, D, F, H, L).

    PLoS ONE Alerts: New Articles

  • Arrow indicates Rols at the site of FCM-precursor/myotube contact.

    PLoS ONE Alerts: New Articles

  • Rols is similarly enriched in vivo at points of FCM-precursor/myotube contact in embryos rescued with Duf flag, Duf ΔCT1-flag, Duf ΔCT2-flag and Duf 4 phos-flag (arrow) but not with Duf ΔCT3-flag

    PLoS ONE Alerts: New Articles

  • Also, conserved putative phosphorylation signalling sites function additively resulting in efficient myoblast fusion and the formation of a mature myotube.

    PLoS ONE Alerts: New Articles

Comments

Log in or sign up to get involved in the conversation. It's quick and easy.