from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A synthetic opioid narcotic, C21H27NO4, used in the form of its hydrochloride as an analgesic.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A synthetic opioid used commercially as an analgesic.


from The American Heritage® Dictionary of the English Language, 4th Edition

[Blend of nalorphine, a narcotic antagonist (short for N-allylnormorphine, its chemical name) and butane.]


  • PenWest Pharmaceuticals slid 95 cents, or 18%, to 4.35, after the drug-delivery technology developer said a Phase IIa clinical trial for nalbuphine, an extended-release drug to treat chronic pain, didn't meet its primary endpoint.

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  • I eeven some the hypnagogic nalbuphine of regiones but that has hypothesized now.


  • The decrease of $2.5 million was primarily due to lower expenses related to the development of nalbuphine ER and other early stage product candidates, as well as lower compensation expense due to staff reductions.


  • We have three primary assets available for license; nalbuphine ER, Opana ex-US, and collaborations utilizing our drug delivery technology.

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  • And then I guess secondarily, is there any benefit to be in charge of those discussions as you also are looking for a partner on nalbuphine?

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  • I don't know - I mean it's certainly something we'll try to do, but most of our nalbuphine efforts really have centered here around the US and we are sort of ways down that path. Home Page

  • This decrease was due to lower contractual payments to Edison, overall lower program spending, primarily due to lower spending on nalbuphine ER and lower operating expenses, partially due to headcount reductions and other expense controls implemented in the first quarter. Home Page

  • So first of all, with regard to nalbuphine, we have had a lot of efforts underway in this area all year, as you know.

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  • We know that nalbuphine is more difficult to partner away, even that's going to get partnered away. Home Page

  • They include morphine (usually used only in early labor to help women get some sleep when this stage of labor is long), meperidine (Demerol or Pethidine), nalbuphine (Nubain), butorphanol (Stadol), and fentanyl (Sublimaze).

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