Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. A drug, C21H25NO3, used as an antagonist to narcotic drugs.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. An opiate derivative used mainly to manage alcoholism.

Etymologies

nal(trexone) + mefene (probably shortening and alteration of methylene).
(American Heritage® Dictionary of the English Language, Fourth Edition)

Examples

  • In three clinical trials involving a total of 2,000 people with alcohol dependence, half the participants were given nalmefene and the other half a placebo pill "on an as-needed basis," Lundbeck said.

    Danish Alcoholism Drug Does Well in Three Clinical Trials

  • Lundbeck's drug, nalmefene, can be taken with alcohol and is being tested as a way to reduce a person's craving for drink.

    Danish Alcoholism Drug Does Well in Three Clinical Trials

  • "All outcomes were consistently in favour of nalmefene compared to placebo, though some were not statistically significant at every single time point," Lundbeck said, meaning they could have been due to chance.

    Danish Alcoholism Drug Does Well in Three Clinical Trials

  • Lundbeck said it isn't currently planning to request U.S. regulatory approval for the drug, nalmefene, because it is an older therapy that doesn't have strong patent protection in the U.S.

    Danish Alcoholism Drug Does Well in Three Clinical Trials

  • He led a study published in "The American Journal of Psychiatry" on the drug nalmefene.

    CNN Transcript Feb 1, 2006

  • TM nalmefene for alcohol dependence was filed in the EU by our partner H.

    Reuters: Press Release

  • In connection with the second quarter report, Lundbeck's President and CEO Ulf Wiinberg said: Again our key products deliver solid growth and during the quarter we received positive and encouraging data from the phase III trials with nalmefene.

    Reuters: Press Release

  • Lundbeck reported positive data from two Phase III studies for its drug nalmefene, which helps curbs alcohol intake.

    MarketWatch.com - Top Stories

  • Lundbeck announced in June the completion of ESENSE2, the last study in its Phase 3 program evaluating nalmefene for the treatment of alcohol dependence.

    Reuters: Press Release

  • Earlier in the year Biotie's partner Lundbeck reported positive data from the Phase 3 program for nalmefene in alcohol dependence and plans to file the drug in Europe by the end of 2011.

    Reuters: Press Release

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