Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • abbr. A segment of non-coding RNA.

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

From non-coding RNA

Examples

  • Seven of the eight "unclassified ncRNA candidates" can be readily annotated as homologs of well-known ncRNAs.

    BioMed Central - Latest articles

  • CCND1 gene [20], and the Evf2 ncRNA (derived from an ultraconserved regulatory region) was shown to act in

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  • To start characterizing the properties of the extragenic transcription described above, we first analyzed kinetics of induction of the corresponding ncRNA relative to that of the downstream coding gene.

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  • Cells were stimulated with LPS+γIFN as indicated. y-axes indicate mRNA (left) or ncRNA (right) levels relative to those of a housekeeping gene (TBP).

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  • LCR, locus control region; lncRNA, long non-coding RNA; ncRNA, non-coding RNA; Pol_II, RNA polymerase II; PRE, polycomb group response element; PWM, position weight matrix; TF, transcription factor; TFBS, transcription factor binding site; TSS, transcription start site

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  • These two catalogues show little overlap, suggesting that each of them includes only a small fraction of a presumably much larger ncRNA repertoire

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  • An example of a specific effect of the transcription process itself, in which the ncRNA product apparently has no direct role, is provided by the

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  • However, we believe that an additional important aspect should be considered in distinguishing enhancers that generate functional RNAs from canonical RNA genes: the local and temporally restricted cis-regulatory role of the enhancer-associated ncRNA (temporal restriction being related to the rapid degradation of these transcripts after they are synthesized).

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  • CpG islands is clearly much lower than observed at protein-coding genes (72%) [55]; however, our results are similar to those reported by Ponjavic et al. for ncRNA genes expressed in mouse development, which were associated with

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  • Overall, the role of ncRNA transcripts versus transcription in conveying regulatory information likely varies depending on the regulatory region considered, and ad hoc experiments will be required to understand the relative frequency of the two groups of mechanisms.

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