necroinflammatory love

necroinflammatory

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. Relating to, or producing necroinflammation

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

From necro- +‎ inflammatory

Examples

  • ALT levels, and a 39 percent relative improvement in biopsy necroinflammatory scores, both measures of liver damage.

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  • C improves surrogate outcomes (alanine aminotransferase levels, histologic changes, and sustained virologic responses), these surrogates have never been validated. 2 In the HALT-C trial, maintenance therapy with peginterferon therapy improved inflammatory markers (alanine aminotransferase levels and necroinflammatory histologic findings) and reduced viral titers (producing more sustained virologic responses) without affecting clinical outcomes.

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  • Histologic improvement (greater than or equal to a two-point decrease in Knodell necroinflammatory score) and improvement in Knodell fibrosis score (greater than or equal to a one-point decrease) were evaluated for patients with biopsies at baseline, Week 48 and Week 148.

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  • Improvement in liver histology was defined as greater than or equal to a two-point decrease in Knodell necroinflammatory score and no worsening of Knodell fibrosis score.

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  • The co-primary long term histology endpoints were the proportion of patients with histologic improvement (defined as greater than or equal to a two-point decrease in Knodell necroinflammatory score and no worsening of Knodell fibrosis score) and the proportion of patients with improvement in Ishak fibrosis score (greater than or equal to a one-point decrease), both compared to baseline.

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