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neoangiogenesis

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. formation of blood vessel in tumor tissue

Etymologies

Sorry, no etymologies found.

Examples

  • Targeting of genes for endothelial growth factors and proteolytic enzymes have been essential for understanding mechanisms of neoangiogenesis and metastasis of solid tumours and are also used for developing therapeutic strategies to prevent spreading [68].

    The 2007 Nobel Prize in Physiology or Medicine - Advanced Information

  • As such, these cells have the potential to move the regenerative medical field beyond the classic paracrine mechanisms neoangiogenesis and down-regulation of inflammation toward tissue and bone repair and regeneration.

  • Circulating endothelial progenitor cells (EPCs), responsible for neoangiogenesis and vascular repair, negatively correlate with vascular dysfunction and atherosclerotic risk factors.

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  • "This strongly suggests neoangiogenesis as the main mechanism of action for these cells."

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  • For instance, DLL4-dependent events, such as tumor neoangiogenesis

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  • (HIF-1alpha), a regulatory factor of angiogenic switch, in comparison to vascular endothelial growth factor A and C (VEGF-A and VEGF-C), recognized to be involved in blood and lymph vessel neoangiogenesis, with potential association in the prognosis of patients with renal cell carcinoma.

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  • (CDC), but may additionally involve direct inhibition of tumor cell migration and neoangiogenesis. y-specific murine monoclonal antibodies and antibody-toxin conjugates were limited by immunogenicity, dose limiting toxicity.

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  • The involvement of Ley in cell adhesion and angiogenic events, together with the high surface densities on Le y-positive cancers, suggest the involvement of this carbohydrate antigen in tumor migration (ie., metastasis) and neoangiogenesis

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