from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun Either of two related white crystalline compounds, C12H19BrN2O2 or C13H22N2O6S, that opposes the action of acetylcholinesterase and is used primarily to treat myasthenia gravis and to counteract muscle atony and muscle relaxants.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun chemistry A
parasympathomimetic, a reversible cholinesterase inhibitor.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- noun a cholinergic drug (trade name Prostigmin) used to treat some ophthalmic conditions and to treat myasthenia gravis
from The American Heritage® Dictionary of the English Language, 4th Edition
There's no one on Ell who would react to the name 'neostigmine' even if he saw the order, except maybe Old Toke himself.
Related molecules, such as neostigmine, do not enter the CNS.
Decreased libido and impaired ejaculation also may occur; they can be treated with dose reduction or a peripheral cholinesterase inhibitor neostigmine, 7.5-15 mg at 30 to 60 minutes prior to intercourse.
With the help of synthetic chemists, morphine has become hydromorphine; lysergic acid has been converted to methylysergide; cocaine has yielded procaine; physostigmine has been converted into neostigmine and salicin has been changed into acetylsalicylic acid.
The neostigmine Seever had sent for seemed to palliate the weakness, which had not been experienced for some time, and the nausea attacks also seemed to have vanished.
"Antibiotics that can cause neuromuscular blockade and possibly exacerbate clinical signs such as aminoglycosides should be avoided, and neurostimulants such as neostigmine should not be used," he cautioned.
Acetylcholine esterase inhibitor (neostigmine): indications: colonic pseudo-obstruction
Analogue of somatostatin (octreotide): experimental evidence of shortening ileus and promoting bowel movements in the small intestine and colon in animal models We believed that neostigmine, which has a focused effect in stimulating large bowel motility, was the most appropriate and beneficial prokinetic agent in this setting (it is also appropriate in patients with colonic pseudo-obstruction).
The median recovery time - the point where half fall above and half fall below - was 2.7 minutes for the sugammadex patients versus 49 minutes for the neostigmine patients.
Study patients getting sugammadex recovered from the muscle relaxers about 17 times faster, on average, than those getting neostigmine.