Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun An inhibitor of dopamine beta-hydroxylase.

Etymologies

Sorry, no etymologies found.

Examples

  • To confirm that the beneficial effects of disulfiram were because of dopamine beta-hydroxylase inhibition, the researchers turned to a drug called nepicastat, which was originally developed for the treatment of congestive heart failure in the 1990s.

    GoodShit

  • The company said it hopes the drug, called nepicastat, will help patients who have lost the ability to accurately assess danger, resulting in a constant sense of alertness.

    Military Top Stories Center

  • Roche has an option on the development and commercialization of SYN120 following an ongoing clinical imaging study using Positron Emission Tomography which is expected to complete in H1 2012. (nepicastat): An orally administered, potent and selective inhibitor of the enzymedopamine beta-hydroxylase (DBH).

    Reuters: Press Release

  • A Phase 2 study of nepicastat in post traumatic stress disorder is ongoing, funded by the US Department of Defense.

    Reuters: Press Release

  • "We reasoned that if disulfiram is really working through dopamine beta-hydroxylase, then nepicastat might be a better alternative."

    GoodShit

  • Researchers at Emory University School of Medicine in Atlanta say nepicastat was tried after the drug disulfiram -- which interferes with the body's ability to metabolize alcohol and results in a bad hangover -- was found to prevent cocaine addiction relapse.

    Latest News - UPI.com

  • To confirm the beneficial effects of dopamine beta-hydroxylase inhibition, researchers turned to the drug nepicastat -- developed in the 1990s to treat congestive heart failure.

    Latest News - UPI.com

  • Initial results about the effectiveness and tolerability of nepicastat are expected next spring, said Synosia spokesman Jan Gregor.

    Military Top Stories Center

  • a Phase I safety trial studying nepicastat for the treatment of cocaine addiction in human subjects.

    GoodShit

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