from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any of a group of proteins associated with neurofibromatosis


Sorry, no etymologies found.


  • NF1 is caused by mutations in a gene called neurofibromin, or Nf1, which makes a protein with the same name.

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  • In additional experiments, Brown showed that reduced levels of neurofibromin affected a different biochemical pathway in brain nerve cells than in peripheral nerve cells.

    WUSTL Record: University News

  • In brain nerve cells, reduced neurofibromin leads to less of a molecule known as cyclic AMP.

    WUSTL Record: University News

  • Because these mice have one defective copy of the NF1 gene, similar to children with neurofibromatosis 1, the cells make fewer copies of the gene's protein, neurofibromin.

    WUSTL Record: University News

  • Her results showed that, unlike peripheral nerve cells, retinal ganglion neurons with less neurofibromin had shorter branches and died more often when stressed.

    WUSTL Record: University News


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