Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun embryology, neurology A free-floating structure generated
in vitro byneural stem cells
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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The neurosphere transplants eventually grew into tumors and reignited the Notch pathway.
PhysOrg.com - latest science and technology news stories 2010
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In agreement with this hypothesis, we find that Nolz1 over-expression promotes cell cycle exit of NPCs in neurosphere cultures and negatively regulates proliferation in telencephalic organotypic cultures.
BioMed Central - Latest articles Noelia Urban 2010
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The neurosphere transplants eventually grew into tumors and reignited the Notch pathway.
Science Blog BJS 2010
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These results may suggest that most cells in the hNPs remain in the PNS precursor state while some intrinsic PNS differentiation is taking place at the periphery of the neurosphere.
PLoS ONE Alerts: New Articles Moran Valensi-Kurtz et al. 2010
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Long-term human neurosphere cultures isolated from brain tissue (gestational 16-20 weeks) have been described previously
PLoS ONE Alerts: New Articles Mitra J. Hooshmand et al. 2009
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This process theoretically selects for a NSC-enriched population; accordingly, these cells exhibit approximately a 2000-fold enhancement in neurosphere initiating capacity
PLoS ONE Alerts: New Articles Mitra J. Hooshmand et al. 2009
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To obtain a direct evidence of the improved self-renewal capacity of T-IhNSC we performed a clonogenic, neurosphere assay.
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In addition to their proliferative capacity, an essential property of bona fide stem cells is their self-renewal potential, which can be demonstrated in neural stem cell cultures by observing a linear cell growth kinetic under the appropriate neurosphere assay conditions and in long-term cultures
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After 4 days in vitro, the fraction of wells positive for neurosphere formation was quantified.
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[18], which enriches the number of cells in the population with neurosphere-initiating capacity approximately 2000-fold.
PLoS ONE Alerts: New Articles Mitra J. Hooshmand et al. 2009
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