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Examples

  • AstraZeneca said an experimental antidepressant that mimics some of nicotine's mood-elevating effects failed in a large clinical trial, a setback for attempts to develop a successor to widely used antidepressants.

    What's News—

  • LONDON—U.K. drug maker AstraZeneca PLC said an experimental antidepressant that mimics some of nicotine's mood-elevating effects failed in a large clinical trial, a setback for the company's attempts to develop a possible successor to today's widely used antidepressants.

    AstraZeneca Dealt Setback on Antidepressant

  • An unexpected drop in weight, blood pressure and respiration was recorded in nicotine subjects and can be partly explained by nicotine's mild anorexic effects, researchers said.

    A New Weapon in the Fight Against Superbugs

  • AstraZeneca, based in the U.K., said it was scrapping further trials of an experimental antidepressant designed to mimic some of nicotine's mood-elevating effects.

    AstraZeneca, Novartis Report Drug Setbacks

  • Targacept has said that TC-5214 lacks nicotine's addictive properties.

    AstraZeneca Dealt Setback on Antidepressant

  • Targacept started out as a subsidiary of R.J. Reynolds, whose scientists spent decades studying nicotine's effects on the body.

    AstraZeneca Dealt Setback on Antidepressant

  • Nicotine is a powerfully reinforcing drug and once the brain becomes dependent on nicotine's presence it is extremely difficult to stop using.

    Barbara Ficarra: States Need Help, Smokers Have Hope

  • Its argument is bolstered by voluminous evidence that the industry has long been aware of nicotine's addictive properties -- a charge the industry denies.

    Firing Up The Politics Of Teen Smoking

  • Named 'Chentix', it works by masquerading as 'nicotine' adequately enough to occupy the brain's 'nicotine's' receptors.

    Why Smokers do not want to quit Smoking?

  • Speak to Nicotine's Sad Grip Recent warnings that the smoking-cessation drug Chantix may cause erratic behavior and suicidal thoughts provide a new window into nicotine's dark and powerful grip on the brain.

    Puff Power: Drug Warnings

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