nitrosoguanidine love

nitrosoguanidine

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. An N-nitroso derivative of guanidine whose methyl derivative is used as a mutagen

Etymologies

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Examples

  • So did X-rays, benzene compounds, and nitrosoguanidine derivatives—all known to cause cancers in rats and mice.

    The Emperor of All Maladies

  • Gotoh T et al. Chemoprevention of N-nitroso-N-methylurea-induced rat mammary carcinogenesis by soy foods or biochanin A. Jpn J Cancer Res 1998; 89: 137-42; Watanabe H et al. Influence of concomitant miso or NaCl treatment on induction of gastric tumors by N-methyl [n-nitro-N-nitrosoguanidine in rats.

    Craig Cooper: Soy: When It's Good, When It's Bad, And How To Tell

  • Slide 24: Induced Mutation Induced Mutation is caused by Base analogs are mutagens. compounds that chemically resemble Chemical mutagens: nucleotide base that Nitrous acid and during DNA replication, nitrosoguanidine that they can be incorporated into the DNA instead of cause chemical the natural base. modifications of purine Intercalating agents are and pyrimidine bases that planar three-ringed alter their hydrogen - molecules that are about bonding properties. the same size as a nucleotide base pair. bromide.

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