from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective Not
from Wiktionary, Creative Commons Attribution/Share-Alike License
John Garthwaite had just reported that nitric oxide was a neuro transmitter in the brain, and we wondered whether or not nitric oxide could be the neurotransmitter in the so called nonadrenergic noncholinergic neurons that were known to innervate the corpus cavernosum smooth muscle.
Our results in mice gastric muscle strips provide visual proof that NO is produced de novo in the nitrergic nerve varicosities upon nonadrenergic noncholinergic (NANC) nerve stimulation.
The EFS was applied under NANC conditions (in the presence of atropine (1 µM) and guanethidine (5 µM)) to block cholinergic and adrenergic responses to elicit nonadrenergic noncholinergic inhibitory responses.
Nitric oxide (NO) has been proposed as a neuromuscular neurotransmitter of nonadrenergic noncholinergic (NANC) inhibitory nerves in the parasympathetic