nondisjunction love

Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun The failure of paired chromosomes or sister chromatids to separate and go to different cells during meiosis.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun genetics The failure of chromosome pairs to separate properly during meiosis

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun meiosis in which there is a failure of paired homologous chromosomes to separate; results in an abnormal number of chromosomes in the daughter cells

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

non- +‎ disjunction

Examples

  • When nondisjunction occurs, the resulting eggs may carry too few or too many chromosomes, a state called aneuploidy.

    Delayed Childbearing

  • Embryos that are trisomic contain, instead of matched pairs of chromosomes, one too many of a given chromosome, most commonly chromosome 13, 18, 21 (which is responsible for Down syndrome), X, or Y. Trisomies are the result of a glitch known as nondisjunction, which occurs principally during the creation of egg cells (although sperm cells may also exhibit such errors).

    Delayed Childbearing

  • Embryos that are trisomic contain, instead of matched pairs of chromosomes, one too many of a given chromosome, most commonly chromosome 13, 18, 21 (which is responsible for Down syndrome), X, or Y. Trisomies are the result of a glitch known as nondisjunction, which occurs principally during the creation of egg cells (although sperm cells may also exhibit such errors).

    Delayed Childbearing

  • When nondisjunction occurs, the resulting eggs may carry too few or too many chromosomes, a state called aneuploidy.

    Delayed Childbearing

  • Shi Q, King RW (2005) Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines.

    PLoS ONE Alerts: New Articles

  • Feingold E, Savage A, Avramopoulos D, Freeman S, et al. (1997) Characterization of susceptible chiasma configurations that increase the risk for maternal nondisjunction of chromosome 21.

    PLoS ONE Alerts: New Articles

  • This makes sense, since these cancers often fail to inactivate the X chromosome, and X chromosome nondisjunction leads to more male worms.

    Ars Technica

  • Most of what goes wrong during meiosis-to-fertilization-to-mitosis results in chromosomal abnormalities, usually nondisjunction, thus providing a mechanism for aneuplodiy -- rather than an insistence that it really does happen.

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  • Koehler KE, Hawley RS, Sherman S, Hassold T (1996) Recombination and nondisjunction in humans and flies.

    PLoS ONE Alerts: New Articles

  • Koehler KE, Hawley RS, Sherman S, Hassold T (1996) Recombination and nondisjunction in humans and flies.

    PLoS ONE Alerts: New Articles

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