nongenotoxic

… The effect of being exposed to a genotoxic material in early childhood is dramatically different from exposure to a nongenotoxic material.

Markets and Majorities Steven M. Sheffrin 1993

In these studies, denufosol was nongenotoxic, noncarcinogenic and induced no observable clinically relevant pulmonary or systemic adverse effects.

Data Presentations at North American Cystic Fibrosis Conference Highlight Denufosol’s Novel Mechanism of Action - Yahoo! Finance 2010

The scientists previously identified other common genetic variants associated with lung cancer risk in NNK disposition pathways, such as CYP2A13, the most active P450 for the phase metabolic activation of NNK and the receptor ADRB2 in its nongenotoxic pathway.

GEN News Highlights 2009