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Examples
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People who undergo nonmyeloablative stem-cell transplants, or "mini transplants," for leukemia, lymp ...
THE MEDICAL NEWS Editors 2010
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Methods We infused autologous CD34+ bone marrow cells transduced with a retroviral vector containing the ADA gene into 10 children with SCID due to ADA deficiency who lacked an HLA-identical sibling donor, after nonmyeloablative conditioning with busulfan.
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"After a mean follow-up of 29.8 months following autologous nonmyeloablative HSCT in patients with newly diagnosed type 1 DM [diabetes mellitus], C-peptide levels increased significantly and the majority of patients achieved insulin independence with good glycemic control."
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Despite the fact that a coordinated effort by modifications in culture technique and administration of nonmyeloablative chemotherapy has markedly improved of the clinical response in melanoma patients, it remains poorly understood why the tumor regression tend to be partial.
PLoS ONE Alerts: New Articles Yo-Ping Lai et al. 2009
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They used a method called autologous nonmyeloablative HSTC (hematopoietic stem cell transplantation) to implant 15 patients with their own stem cells.
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After transfection of the cells with the gene, the cells are re-infused back into the patients after nonmyeloablative conditioning with busulfan.
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Methods We infused autologous CD34+ bone marrow cells transduced with a retroviral vector containing the ADA gene into 10 children with SCID due to ADA deficiency who lacked an HLA-identical sibling donor, after nonmyeloablative conditioning with busulfan.
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The procedure, called autologous nonmyeloablative hematopoietic stem cell transplantation
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Methods We infused autologous CD34+ bone marrow cells transduced with a retroviral vector containing the ADA gene into 10 children with SCID due to ADA deficiency who lacked an HLA-identical sibling donor, after nonmyeloablative conditioning with busulfan.
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Methods We infused autologous CD34+ bone marrow cells transduced with a retroviral vector containing the ADA gene into 10 children with SCID due to ADA deficiency who lacked an HLA-identical sibling donor, after nonmyeloablative conditioning with busulfan.
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