from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. Not synonymous


Sorry, no etymologies found.


  • Four novel nonsynonymous mutations were detected, one of which would produce premature termination of translation c.2686CT p.

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  • They measured the fitness effect of the mutations as a ratio between synonymous (Ks) and nonsynonymous (Ka) amino acid substitutions (so they sequenced 13 mitochondrial genes and counted substitutions).

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  • As a longtime sometime magician, I want to point out that distraction and misdirection are overlapping but nonsynonymous.

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  • Missense mutations or nonsynonymous mutations is where a nucleotide is changed which results in a different amino acid.

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  • For each transmission pair, selection within individuals was quantified using the ratio of nonsynonymous to synonymous substitutions (ω = dN/dS).

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  • Moreover, we identified that plasmid conjugative transfer genes and antibiotic resistance genes are more likely to suffer from positive selection, as indicated by the elevated rates of nonsynonymous substitution.

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  • WDFY4 is a huge protein with unknown function but is predominantly expressed in primary and secondary immune tissues, and a nonsynonymous SNP in this gene was found to be highly associated with SLE susceptibility.

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  • An automated routine identifying human nonsynonymous SNP amino acid missense substitutions for any MHC gene mined the NCBI SNP data base.

    BioMed Central - Latest articles

  • Sunyaev S, Hanke J, Aydin A, Wirkner U, Zastrow I, et al. (1999) Prediction of nonsynonymous single nucleotide polymorphisms in human disease-associated genes.

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  • Bickerton GR, Schreyer A, Forman JR, Cheng TM, et al. (2007) A structural bioinformatics approach to the analysis of nonsynonymous single nucleotide polymorphisms (nsSNPs) and their relation to disease.

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