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- n. 4-methyl-5-(2-pyrazinyl)-3-dithiolethione, a schistosomicide drug also used in tumour prevention.
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Although it is unknown whether or not the strong side effects observed in clinical trials of oltipraz in cancer chemoprevention
Surprisingly, the levels of these free radicals in cardiomyocytes treated with oltipraz were even higher than that treated with angiotensin II, a most important factor in the pathogenesis of hypertrophic cardiomyopathy
 is caused by the unexpected pro-oxidative effect of oltipraz, clearly the ability of oltipraz to treat cardiovascular diseases seems to be limited.
Unlike dh404, we observed that oltipraz, another established Nrf2 activator, induced dramatic increases in superoxide and peroxynitrite generation in cardiomyocytes (