Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun genetics one of two or more homologous gene sequences found in different species

Etymologies

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Examples

  • We found that the effect of RNAi on the mitotic index was most prominent in the case of the two siRNAs directed against the human orthologue of Mgc81475 (huMgc81475).

    PLoS ONE Alerts: New Articles Vincent Gache et al. 2010

  • Mitotic index in HeLa cells treated with siRNA against the human orthologue of Mgc81475.

    PLoS ONE Alerts: New Articles Vincent Gache et al. 2010

  • Furthermore, we showed that transfection of HeLa cells with siRNAs, corresponding to the human orthologue of Mgc81475 dramatically perturbs spindle formation in HeLa cells.

    PLoS ONE Alerts: New Articles Vincent Gache et al. 2010

  • Knocking-down the human orthologue of Mgc81475 clearly implicated this protein in the microtubule stabilization in mitosis.

    PLoS ONE Alerts: New Articles Vincent Gache et al. 2010

  • Furthermore, we showed that transfection of HeLa cells with siRNAs, corresponding to the human orthologue of Mgc81475 dramatically perturbs spindle formation in HeLa cells.

    PLoS ONE Alerts: New Articles Vincent Gache et al. 2010

  • Xenopus orthologue of the C. elegans protein Smu-1 suppressor of mec-8 and unc-52, which is believed to regulate the alternative splicing of pre-mRNAs

    PLoS ONE Alerts: New Articles Vincent Gache et al. 2010

  • LRP5, together with LRP6, is the human orthologue of the

    PLoS ONE Alerts: New Articles Jochen Schulze et al. 2010

  • AKAP5, also referred to as AKAP150 in rodents, is an orthologue of human AKAP79 and bovine AKAP75 and is highly expressed in brain

    PLoS ONE Alerts: New Articles Michael Weisenhaus et al. 2010

  • In line with this reasoning, the closest human orthologue of Xnf7 - TRIM69 (42% identity to Xnf7) - was not reported for MSP

    PLoS ONE Alerts: New Articles Vincent Gache et al. 2010

  • Mgc68500's closest orthologue in man is intracellular hyaluronan-binding protein IHBP4 (HABP4) [68], reminding another hyaluronan-related protein, RHAMM, which participates in Ran-dependent spindle assembly

    PLoS ONE Alerts: New Articles Vincent Gache et al. 2010

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