from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A protein found in bone and dentin, manufactured by osteoblasts. It plays a role in mineralization and calcium ion homeostasis.


Sorry, no etymologies found.


  • Early this year, Dr. Karsenty's team published a study demonstrating that in mice a protein called osteocalcin, which is produced by bone-forming cells called osteoblasts, binds to a specific receptor on cells of the testes.

    NYT > Home Page

  • The first clue that the skeleton may have an important role in regulating blood glucose came in 2007 when Dr. Karsenty discovered that a hormone released by bone - known as osteocalcin - can regulate glucose levels. - latest science and technology news stories

  • The mechanics of vitamin K2 are that it activates a bone protein called osteocalcin, which binds calcium in the bones, thus preventing calcium from moving into the bloodstream and being deposited in the arteries, with often fatal consequences.


  • For our bones to be optimally healthy, one of the proteins found in bone-a protein called osteocalcin-needs to be chemically altered through the process of carboxylation.

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  • Vitamin K, abundant in these plants, plays a role in building the bone protein osteocalcin and binding calcium to the bone matrix.

    Carrie Wiatt, M.S.: Keep Your Bones Strong After Menopause

  • Besides the gamma-carboxylation of osteocalcin, a protein believed to be involved in bone mineralization, there is increasing evidence that vitamin K positively affects calcium balance, a key mineral in bone metabolism.

    Forever Young

  • Experiments show that total GH secretion is increased by about 10% with sodium bicarbonate supplementation and in addition osteocalcin levels are increased.

    6-Week Cure blog idea | The Blog of Michael R. Eades, M.D.

  • In both cases, the fossil taxon proved to have osteocalcin sequences that were, firstly, identical to those of its congeneric living relative (B. bison and H. sapiens respectively), and, secondly, distinctly different from those of related genera (Bos in the case of Bison, and Pan, Gorilla and Pongo in the case of Homo).

    Archive 2006-03-01

  • I think this has the potential to be something pretty big, IF osteocalcin really does prove as resistant, accessible and widespread among fossils as has been implied.

    Archive 2006-03-01

  • Sequence preservation of osteocalcin protein and mitochondrial DNA in bison bones older than 55 ka.

    Archive 2006-03-01


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