Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A sialopontin found in bone tissue

Etymologies

Sorry, no etymologies found.

Examples

  • The protein called osteopontin (OPN) could lead to a novel approach to the treatment of a devastating lung disease.

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  • The team has identified specific genes, such as osteopontin, that are directly induced by LSF.

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  • The serum osteopontin level might be useful in screening asbestos-exposed people for mesotheliomaThe level of soluble mesothelin-related protein is elevated in the serum of about 75% of patients at diagnosis and it has been suggested that it may be useful for screening.

    Balkinization

  • "Osteopontin is a key player in regulating tumor development and progression and the identification of a master regulator of osteopontin, such as LSF, is a very important discovery," said Sarkar.

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  • After years of pilot production, Arla Foods Ingredients is commercialising a milk protein, osteopontin, for the infant formula market that is found in high quantities in human milk.

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  • "Several years ago we discovered that three SIBLINGs-osteopontin, bone sialoprotein and dentin sialophosphoprotein-were expressed at significantly high levels in oral cancers," said Dr. Kalu Ogbureke, an oral and maxillofacial pathologist in the MCG School of Dentistry.

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  • Genetically removing the osteopontin protein prevents lung diseases

    THE MEDICAL NEWS

  • Allan AL, Wilson SM, Hota C, Vantyghem SA, et al. (2003) Beta (3) integrin expression increases breast carcinoma cell responsiveness to the malignancy-enhancing effects of osteopontin.

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  • Nasu K, Ishida T, Setoguchi M, Higuchi Y, Akizuki S, et al. (1995) Expression of wild-type and mutated rabbit osteopontin in Escherichia coli, and their effects on adhesion and migration of P388D1 cells.

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  • Mi Z, Guo H, Wai PY, Gao C, Kuo PC (2006) Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells.

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