Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • v. Simple past tense and past participle of overexpress.
  • adj. Produced by overexpression

Etymologies

Sorry, no etymologies found.

Examples

  • In parallel, they discovered that 12 genes in that region were consistently "overexpressed" - making abnormal amounts of protein - as a result of amplification.

    THE MEDICAL NEWS

  • But when DHR96 was overexpressed, meaning there were higher levels of the protein, it led to increased TAG levels and made the flies more prone to being overweight.

    PhysOrg.com - latest science and technology news stories

  • "overexpressed" the dlk-1 gene in worms - making it more active than normal - broken nerves in the worms regenerated much more quickly than expected.

    Health News from Medical News Today

  • In some cancers, a protein known as bcl-2 is overexpressed.

    A Look at the Inner Life of a Doomed Cell

  • FGF23, a blood protein, is “overexpressed” in oncogenic osteomalacia.

    After the Diagnosis

  • And when the gene was overexpressed, the current rose by as much as 300-fold making a tap of the finger seem like a hammer blow.

    Why Does It Hurt So Bad?

  • Whereas DNA analysis reveals genetic mutations written into a person's genome, RNA analysis reveals which genes are actively overexpressed or underexpressed compared with the general population.

    The Full Feed from HuffingtonPost.com

  • Therapeutics that use RNA interference, or "RNAi," have great promise because of their ability to "silence," or down-regulate, the expression of a specific gene that may be overexpressed in a disease condition.

  • As a reminder, in May 2010, CytRx initiated a Phase II proof-of-concept clinical trial ENABLE with bafetinib as a second line treatment for B-CLL due to the potent and specific inhibitory properties of bafetinib against Lyn and Fyn kinases, which are overexpressed in B-CLL cancers.

  • His current research includes studies in transgenic mice to elucidate the requirements for inducing therapeutically effective T-cell responses to self-proteins that are overexpressed in tumors, development of genetically-modified mice to better model human immune responses to facilitate the development of vaccines for HIV and cancer, genetic modification of T cells to improve efficacy in adoptive therapy, and clinical trials for the treatment of leukemia with adoptive T-cell therapy.

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