from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun A salt or an ester of oxaloacetic acid.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun organic chemistry any
saltor esterof oxaloacetic acid
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- noun a salt or ester of oxalacetic acid
from The American Heritage® Dictionary of the English Language, 4th Edition
from Wiktionary, Creative Commons Attribution/Share-Alike License
Gluconeogenesis consumes oxaloacetate, which is essential for the entry of Acetyl CoA into the Krebs cycle.
Hence the body probably will prefer the amino acid et al --oxaloacetate-- glucose pathway first.
Upon more thinking, oxaloacetate is also a precursor to glucose.
When supplies of oxaloacetate are low, the liver converts the increasing levels of Acetyl CoA into ketone bodies.
Only when the body is sated with glucose will the oxaloacetate then be used by the kreb cycle= end of ketosis.
Entner-Doudoroff pathway, of oxaloacetate formation via the citrate cycle, and of amino acid biosynthesis suggest that both regulators trigger the central metabolism of Y. enterocolitica.
Thus, the role of Hfq appears to be at most marginal for the virulence of SCHU S4 but considering that the difference compared to the parental strain was marginal also in subspecies holarctica, the contribution of Hfq may not be distinct between subspecies Gluconeogenesis in the absence of pyruvate requires the functions of phosphoenolpyruvate carboxykinase (PEPCK), encoded by pckA, which catalyses the decarboxylation and phosphorylation of oxaloacetate to form phosphoenolpyruvate (PEP) .
The data imply that PEPC is critically involved in replenishing the oxaloacetate pool in the citrate cycle under virulence conditions.
Activities enzymes concerned pyruvate oxaloacetate metabolism heart liver developing sheep
My understanding (and your GREAT elucidations on a lot of medical explanations-thank you) is that Acetyl CoA will enter the mitochondria (kreb cycle) if and only if oxaloacetate (made directly from some amino acids and indirectly thru glycerol,some a.a.’s and glucose via pyruvate ) is present.