Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun organic chemistry Any of a class of heterocyclic ketones, derived from oxazolidine, useful in organic synthesis

Etymologies

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Examples

  • It has developed several types of resistance to vancomycin, a glycopeptide, which for decades was the MRSA drug of last resort, and is beginning to exhibit resistance to drugs in newly developed families that were intended to replace vancomycin: linezolid (Zyvox), an oxazolidinone, and daptomycin (marketed as Cubicin), a lipopeptide.

    SUPERBUG MARYN MCKENNA 2010

  • It has developed several types of resistance to vancomycin, a glycopeptide, which for decades was the MRSA drug of last resort, and is beginning to exhibit resistance to drugs in newly developed families that were intended to replace vancomycin: linezolid (Zyvox), an oxazolidinone, and daptomycin (marketed as Cubicin), a lipopeptide.

    SUPERBUG MARYN MCKENNA 2010

  • It has developed several types of resistance to vancomycin, a glycopeptide, which for decades was the MRSA drug of last resort, and is beginning to exhibit resistance to drugs in newly developed families that were intended to replace vancomycin: linezolid (Zyvox), an oxazolidinone, and daptomycin (marketed as Cubicin), a lipopeptide.

    SUPERBUG MARYN MCKENNA 2010

  • The company's lead investigational drug, tedizolid phosphate, is an IV and orally administered second generation oxazolidinone in Phase 3 clinical development for the treatment of ABSSSI.

    unknown title 2011

  • The company's lead investigational drug, torezolid phosphate, is an IV and orally administered second generation oxazolidinone in Phase 3 clinical development for the treatment of ABSSSI, the first such trial to be initiated under a Special Protocol Assessment SPA.

    unknown title 2011

  • The company's lead investigational drug, tedizolid phosphate, is a once daily, IV and orally administered second generation oxazolidinone in Phase 3 clinical development for the treatment of ABSSSI.

    unknown title 2012

  • The company's lead investigational drug, tedizolid phosphate, is a once daily, IV and orally administered second generation oxazolidinone in Phase 3 clinical development for the treatment of ABSSSI.

    unknown title 2012

  • The company's lead investigational drug, torezolid phosphate, is an IV and orally administered second generation oxazolidinone in Phase 3 clinical development for the treatment of acute bacterial skin and skin structure infections (ABSSSI), the first such trial to be initiated under a Special Protocol Assessment (SPA).

    Trius Hires Chief Commercial Officer - Yahoo! Finance 2011

  • In December 2010, research was published elucidating the mechanism by which an investigational second generation oxazolidinone called torezolid phosphate retains full activity against clinical isolates of Staphylococcus aureus carrying the cfr gene.

    unknown title 2011

  • Torezolid phosphate is an IV and orally administered second generation oxazolidinone currently being developed by Trius Therapeutics in Phase 3 clinical trials for the treatment of serious gram-positive infections, including those caused by methicillin-resistant Staphylococcus aureus, or MRSA.

    unknown title 2011

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