Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any of a class of heterocyclic ketones, derived from oxazolidine, useful in organic synthesis

Etymologies

Sorry, no etymologies found.

Examples

  • It has developed several types of resistance to vancomycin, a glycopeptide, which for decades was the MRSA drug of last resort, and is beginning to exhibit resistance to drugs in newly developed families that were intended to replace vancomycin: linezolid (Zyvox), an oxazolidinone, and daptomycin (marketed as Cubicin), a lipopeptide.

    SUPERBUG

  • The company's lead investigational drug, tedizolid phosphate, is a once daily, IV and orally administered second generation oxazolidinone in Phase 3 clinical development for the treatment of ABSSSI.

  • In December 2010, research was published elucidating the mechanism by which an investigational second generation oxazolidinone called torezolid phosphate retains full activity against clinical isolates of Staphylococcus aureus carrying the cfr gene.

  • Torezolid phosphate is an IV and orally administered second generation oxazolidinone currently being developed by Trius Therapeutics in Phase 3 clinical trials for the treatment of serious gram-positive infections, including those caused by methicillin-resistant Staphylococcus aureus, or MRSA.

  • The company's lead investigational drug, torezolid phosphate, is an IV and orally administered second generation oxazolidinone in Phase 3 clinical development for the treatment of ABSSSI, the first such trial to be initiated under a Special Protocol Assessment SPA.

  • The company's lead investigational drug, tedizolid phosphate, is an IV and orally administered second generation oxazolidinone in Phase 3 clinical development for the treatment of ABSSSI.

  • The company's lead investigational drug, torezolid phosphate, is an IV and orally administered second generation oxazolidinone in Phase 3 clinical development for the treatment of acute bacterial skin and skin structure infections (ABSSSI), the first such trial to be initiated under a Special Protocol Assessment (SPA).

    Trius Hires Chief Commercial Officer - Yahoo! Finance

  • Business Unit where he was directly responsible for the U.S. commercial strategy for products with over $1.5 billion in annual U.S. sales including the first generation oxazolidinone

    Trius Hires Chief Commercial Officer - Yahoo! Finance

  • "Trius provides a unique opportunity to launch torezolid phosphate, a best-in-class oxazolidinone, and to contribute to the development of its preclinical portfolio," stated

    Trius Hires Chief Commercial Officer - Yahoo! Finance

  • Zyvox (Linezolid) is an oxazolidinone antibiotic used to treat certain serious bacterial infections.

    CertCities.com | IT Forums

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