Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective biology Between
cells
Etymologies
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Examples
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Endothelial tight and adherens junctions control a variety of physiological processes like adhesion, paracellular transport of solutes or trafficking of activated leukocytes.
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Conclusions pCPT-cAMP and, to a lesser extend, 8-Br-cAMP/Na improved formation of continuous tight junction strands and decreased paracellular permeability in primary HUVEC.
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Pezzicoli A, Santi I, Lauer P, Rosini R, Rinaudo D, et al. (2008) Pilus backbone contributes to group B Streptococcus paracellular translocation through epithelial cells.
PLoS ONE Alerts: New Articles Cira Daniela Rinaudo et al. 2010
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Pezzicoli A, Santi I, Lauer P, Rosini R, Rinaudo D, et al. (2008) Pilus backbone contributes to group B Streptococcus paracellular translocation through epithelial cells.
PLoS ONE Alerts: New Articles Cira Daniela Rinaudo et al. 2010
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We further demonstrated that although all compounds induced protein kinase A-dependent expression of the tight junction proteins claudin-5 and occludin only pCPT-cAMP slightly enhanced paracellular barrier functions.
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The TPE system allows its drug cargo to cross mucosal epithelia in the small intestine by inducing a temporary opening of the Tight Junctions that seal and regulate passage between cells (the paracellular route).
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We here compared the effect of cyclic 3'-5'-adenosine monophosphate (cAMP) and its derivates on formation and stabilization of tight junctions and on alterations in paracellular permeability in HUVEC.
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Inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), are multi-factorial diseases typically associated with relapsing diarrhea, which is caused by increased paracellular permeability of the intestinal epithelial lining and an intestinal hyperosmotic environment
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Although ZO-1 is not the only tight junction protein responsible for paracellular barrier sealing, it plays a central role in maintenance of paracellular intestinal barrier integrity by connection of the intercellular tight junction proteins
PLoS ONE Alerts: New Articles Tim G. A. M. Wolfs et al. 2009
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[8], but also for the existence of skin barrier function by regulating the selective permeability of the paracellular pathway
PLoS ONE Alerts: New Articles Tammy-Claire Troy et al. 2009
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