Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. Between cells

Etymologies

Sorry, no etymologies found.

Examples

  • Pezzicoli A, Santi I, Lauer P, Rosini R, Rinaudo D, et al. (2008) Pilus backbone contributes to group B Streptococcus paracellular translocation through epithelial cells.

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  • The TPE system allows its drug cargo to cross mucosal epithelia in the small intestine by inducing a temporary opening of the Tight Junctions that seal and regulate passage between cells (the paracellular route).

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  • Endothelial tight and adherens junctions control a variety of physiological processes like adhesion, paracellular transport of solutes or trafficking of activated leukocytes.

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  • Conclusions pCPT-cAMP and, to a lesser extend, 8-Br-cAMP/Na improved formation of continuous tight junction strands and decreased paracellular permeability in primary HUVEC.

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  • We further demonstrated that although all compounds induced protein kinase A-dependent expression of the tight junction proteins claudin-5 and occludin only pCPT-cAMP slightly enhanced paracellular barrier functions.

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  • We here compared the effect of cyclic 3'-5'-adenosine monophosphate (cAMP) and its derivates on formation and stabilization of tight junctions and on alterations in paracellular permeability in HUVEC.

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  • Inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), are multi-factorial diseases typically associated with relapsing diarrhea, which is caused by increased paracellular permeability of the intestinal epithelial lining and an intestinal hyperosmotic environment

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  • Although ZO-1 is not the only tight junction protein responsible for paracellular barrier sealing, it plays a central role in maintenance of paracellular intestinal barrier integrity by connection of the intercellular tight junction proteins

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  • [8], but also for the existence of skin barrier function by regulating the selective permeability of the paracellular pathway

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