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Examples
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The advent of pathotropic (disease-seeking) targeting technology first enabled the development of tumor-targeted Rexin-G, which seeks-out, accumulates-in, and selectively delivers a lethal designer gene to tumors that have spread throughout the body (metastatic cancer), halting the progression of disease while improving both survival and quality-of-life.
Medindia Health News 2010
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The finding that miR-121 targets Cyclin G1 gene expression confirms that Rexin-G may indeed be restoring a natural tumor suppressor function that is lost in the development and progression of many types of cancer; while the pathotropic (or disease-seeking) properties of Rexin-G function to deliver this agreeably rational and strategic anti-cancer agent precisely where it is needed most.
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