Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A particular
drug used inchemotherapy .
Etymologies
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Examples
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Other approved therapies, such as pemetrexed (Alimta ™) are indicated for non-squamous NSCLC only. 3
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Other approved therapies, such as pemetrexed (Alimta ™) are indicated for non-squamous NSCLC only. 2
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ONX 0801 is distinct from currently marketed thymidylate synthase inhibitors such as pemetrexed, 5 fluorouracil, and capecitabine because of its selective tumor cell uptake by the alpha-folate receptor but is similar in its intracellular mechanism of action.
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ONX 0801 is distinct from currently marketed thymidylate synthase inhibitors such as pemetrexed, 5 fluorouracil, and capecitabine because of its selective tumor cell uptake by the alpha-folate receptor but is similar in its intracellular mechanism of action.
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For patients unable to tolerate pemetrexed, cisplatin in combination with gemcitabine or vinorelbine is an alternative, although a survival benefit has not been shown for these drugs.
Balkinization 2007
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Cisplatin in combination with raltitrexed has shown an improvement in survival similar to that reported for pemetrexed in combination with cisplatin, but raltitrexed is no longer commercially available for this indication.
Balkinization 2007
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Some side effects such as nausea and vomiting, stomatitis, and diarrhoea were more common in the combination pemetrexed group but only affected a minority of patients and overall the combination of pemetrexed and cisplatin was well tolerated when patients received vitamin supplementation; both quality of life and lung function tests improved in the combination pemetrexed group.
Balkinization 2007
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In February 2004, the United States Food and Drug Administration approved pemetrexed for treatment of malignant pleural mesothelioma.
Balkinization 2007
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Vitamin supplementation was given to most patients in the trial and pemetrexed related side effects were significantly less in patients receiving pemetrexed when they also received daily oral folate 500mcg and intramuscular vitamin B12 1000mcg every 9 weeks compared with patients receiving pemetrexed without vitamin supplementation.
Balkinization 2007
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In February 2004, the United States Food and Drug Administration approved pemetrexed for treatment of malignant pleural mesothelioma.
Balkinization 2007
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