Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun Plural form of
peptidoglycan .
Etymologies
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Examples
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Dworkin noted that the immune systems of animals recognize the presence of foreign invaders in a similar way, by detecting chains of muropeptide (called peptidoglycans).
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Rethage J, Seibl R, Lauener R, Gay RE, et al. (2003) Bacterial peptidoglycans but not CpG oligodeoxynucleotides activate synovial fibroblasts by toll-like receptor signaling.
PLoS ONE Alerts: New Articles Hans-Christian Ingerslev et al. 2010
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Endocrine reviews 24: 488. van der Heijden IM, Wilbrink B, Tchetverikov I, Schrijver IA, Schouls LM, et al. (2000) Presence of bacterial dna and bacterial peptidoglycans in joints of patients with rheumatoid arthritis and other arthritides.
PLoS ONE Alerts: New Articles Gang Wu et al. 2010
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The activation of this immune pathway is triggered by peptidoglycans - sugars found on the bacterial wall - and results in the activation of a molecule called Relish.
Scientific Blogging 2008
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Since peptidoglycans are widely present in bacteria the next question would be to find if the regulatory system here described applies to other host-microorganisms interactions, including those involving humans.
Scientific Blogging 2008
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"The recognition of peptidoglycans is central to innate immunity," he said.
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Polymer Assembly The enzyme peptidoglycan glycosyltransferase (PGT) synthesizes peptidoglycans for bacterial cell walls by stringing together a substrate that consists of a disaccharide with a pentapeptide and a C
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Results from microscopic observation and separation of the cell's soluble and insoluble components suggested, however, that PIMS acted, not by destroying PGRP-LCx but by misplacing it, away from its usual localisation - the plasma membrane - resulting in an incapability of the immune system to see peptidoglycans and consequently of getting activated.
Scientific Blogging 2008
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As PGRP-LCx recognition of peptidoglycans activates Imd and ultimately Relish, the outcome of the interaction with Pims is lack of availability to peptidoglycans and consequently suppression of the (Imd) immune response.
Scientific Blogging 2008
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"Friendly" bacteria, on the other hand, despite containing peptidoglycans in their wall exist peacefully inside Drosophila's gut.
Scientific Blogging 2008
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