perifosine

Bentsur added that KERX would consider licensing its colon cancer drug, known as perifosine, or perhaps even sell the drug on its own.

unknown title 2011

They have their product, which is called perifosine, in Phase III development for multiple myeloma, where they have already seen robust Phase II data in relapsed refractory multiple myeloma, MM, patients.

A 2010 Health Care Review Looks At Ladenburg Thalmann Biotech Stock Picks: Did You Buy Them In April? - Yahoo! Finance 2010

In the current study, researchers looked at a drug called perifosine, which inhibits the Akt pathway.

THE MEDICAL NEWS 2009

AEterna Zentaris, said the Food and Drug Administration plans to expedite its review of their colorectal cancer treatment perifosine.

Swift Energy and Beazer Move Higher; Arena Up Too Kristina Peterson 2010

AEterna Zentaris, said the Food and Drug Administration plans to expedite its review of their colorectal cancer treatment perifosine.

Swift Energy and Beazer Move Higher; Arena Up Too Kristina Peterson 2010

AEterna Zentaris, said the Food and Drug Administration plans to expedite its review of their colorectal cancer treatment perifosine.

Swift Energy and Beazer Move Higher; Arena Up Too Kristina Peterson 2010

Juergen Engel, Ph.D., Aeterna Zentaris' President and Chief Executive Officer, commented: As part of our targeting strategy in cancer with perifosine, AEZS-108, AEZS-112 and AEZS-120, we are proud to have identified the first in class Erk 1/2 inhibitor with in vivo anticancer activity.

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Keryx is developing KRX-0401 (perifosine), a novel, potentially first-in-class, oral anti-cancer agent that inhibits Akt activation in the phosphoinositide 3-kinase (PI3K) pathway, and also affects other signal transduction pathways, including the JNK pathway, believed to be associated with cell death, growth, differentiation and survival.

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Hopefully, Aeterna and Keryx haven't jinxed the perifosine by naming the phase 3 trial "X-PECT" Xeloda + Perifosine Evaluation in Colorectal cancer Treatment.

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Early development of the Erk inhibitor AEZS-131 is an integral part based on our knowledge with perifosine of Aeterna Zentaris' kinase research program comprising the investigation of different compounds for single Erk inhibition, single PI3K inhibition and dual Erk/PI3K kinase inhibition.

unknown title 2011