from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. The cell body of a neuron, containing the nucleus and organelles.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. The cell body of a neuron or of an odontoblast

from The Century Dictionary and Cyclopedia

  • n. The cell-body or cytoplasm of a nerve-cell, or neurone, as distinguished from its nucleus and its processes, the dendrites and neuraxon. The perikaryon consists of a twofold substance — an achromatic, fibrillar spongioplasm, regarded as conductive in function, and a trophoplasmic ground-substance, regarded as the seat of metabolic chemical changes.


peri- + Greek karuon, nut; see karyo-.
(American Heritage® Dictionary of the English Language, Fourth Edition)


  • CWD infection was confirmed in all cases by the presence of histologic lesions in the brain including spongiform degeneration of the perikaryon, the immunohistochemical detection of disease-associated PrP in brain and tonsil, or by immunoblotting of protease-resistant, disease associated PrP (CerPrPSc).



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