phenazopyridine love

phenazopyridine

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A chemical used as an analgesic for the urinary tract.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. analgesic (trade name Pyridium) used to treat urinary tract infections

Etymologies

Sorry, no etymologies found.

Examples

  • The blue color of methylene blue may impart a transitory cyanosis to the patient which clears as the methylene blue is converted to the active and colorless leukomethylene blue. 1 It is theoretically possible that repeat doses may be required in phenazopyridine ingestions due to persistent and prolonged production of toxic metabolites.

    Phenazopyridine

  • Although toxicity with phenazopyridine is relatively uncommon, when it does occur, it may present with a varied and potentially serious clinical picture.

    Phenazopyridine

  • Methemoglobinemia is a serious complication which can occur with acute phenazopyridine ingestions.

    Phenazopyridine

  • The mechanism for hemolytic anemia with phenazopyridine use has not been described.

    Phenazopyridine

  • Acute haemolytic anaemia due to phenazopyridine hydrochloride in G-6-PD deficiency subject.

    Phenazopyridine

  • Transient acute oliguric13,14 or nonoliguric15,16 renal failure may be seen with large doses13,15,16 or prolonged use14 of phenazopyridine.

    Phenazopyridine

  • Hemolytic anemia has been reported with chronic therapeutic use2-6 and with acute overdoses7 of phenazopyridine and may be the only sign of toxicity.

    Phenazopyridine

  • Because neonates have both an immature NADH-dependent methemoglobin reductase system and higher levels of fetal hemoglobin,11-12 they are more susceptible to the oxidative stresses which can be seen with phenazopyridine.

    Phenazopyridine

  • In the case presented, the only symptom of phenazopyridine toxicity observed was cyanosis with profound methemoglobinemia.

    Phenazopyridine

  • Rarely have patients with normal renal function developed acute renal failure. 13,16 Renal toxicity due to phenazopyridine may be a direct effect of the drug and/or its metabolites, or may be secondary to hypoxic injury when methemoglobinemia occurs. 13 Treatment is usually supportive.

    Phenazopyridine

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