Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A diterpene derived from croton oil

Etymologies

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Examples

  • Seed collection toxins, such as phorbol esters,4 adding to its value.

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  • My period in Freiburg permitted me to also work on other aspects of tumour virology: I discovered the potent activity of some phorbol esters in inducing latent Epstein-Barr virus DNA.

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  • D. and EVANS, F.J. (1974) A quantitative gas-liquid chromatographic method for phorbol and related diterpenes as their acetates.

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  • GSCHW EN DT, M. and HECKER, E. (1969) Tumour-promoting compounds from Euphorbia triangularis: mono-and diesters of 12-desoxy-phorbol.

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  • The chip was used to study the immune response of pigs following stimulation of porcine peripheral blood mononuclear cells (PBMCs) with lipopolysaccharide (LPS) or a mixture of phorbol myristate acetate (PMA) and ionomycin for 24 hours.

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  • Using phorbol myristate acetate (PMA), it is possible to overcome this block in THP-1 cells (an M5-AML containing the MLL-MLLT3 fusion), resulting in differentiation to an adherent monocytic phenotype.

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  • In murine pre-B and mouse T-cell hybridoma cell lines, optineurin expression was upregulated by tumor necrosis factor α (TNFα) and interferon and its phosphorylation was induced upon phorbol 12-myristate 13-acetate (PMA) stimulation

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  • (N-formylmethionyl-leucyl-phenylalanine [fMLP] and phorbol 12-myristate 13-acetate [PMA]) or a combination of a priming and an activating agonist.

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  • In contrast, phorbol esters induce Duox2 phosphorylation via protein kinase C activation associated with high H

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  • This process can be modeled in vitro by exposing cells to chemical tumor promoters, phorbol esters and octylindolactam-V (OI-V), known to activate protein kinase C

    BioMed Central - Latest articles

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