Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun Plural form of
phosphatase .
Etymologies
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Examples
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When phosphate levels are low in surface waters, phytoplankton excrete extracellular enzymes called alkaline phosphatases, which have the ability to free phosphate bound to organic molecules.
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Receptor protein-tyrosine phosphatases: origin of domains catalytic domain, Ig-related domain, fibronectin type III module based on the sequence of the sponge Geodia cydonium.
Stuck on you, biological Velcro and the evolution of adaptive immunity - The Panda's Thumb 2006
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I have tried to describe your field of research and elegant discoveries in your studies of reversible protein phosphorylation, going back to the initial detection of the activation mechanism of phosphorylase, and continuing with protein phosphatases.
The Nobel Prize in Physiology or Medicine 1992 - Presentation Speech 1997
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Their counterparts, the phosphatases, are equally essential in the extended cascade.
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In addition, the system includes a large number of phosphatases, which in an opposite manner regulate the removal of the protein phosphate groups from proteins.
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Imbalance between kinases and phosphatases can cause disease and nondesirable tissue reactions.
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Blood pressure, the inflammatory reaction, and brain signal transduction - just to name a few examples - are being regulated through different hormonal interactions and these interactions in turn are mediated through kinases and phosphatases.
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MptpB, a virulence factor from Mycobacterium tuberculosis, has phosphoinositide phosphatase activity and a distinct active site P-loop signature HCXXGKDR that shares characteristics with eukaryotic lipid phosphatases and protein tyrosine phosphatases.
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This study provides a foundation for examining the biological role of this new family of phosphatases and their potential as pharmaceutical targets against infectious diseases.
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Phosphoinositide phosphatases from bacterial pathogens are therefore key players in this modulation and constitute attractive targets for chemotherapy.
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