Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. Any of many biologically active compounds in which two alcohols form ester bonds with phosphate
Etymologies
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Examples
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Ensuing discoveries of other natural catalytic RNAs that could cleave and ligate phosphodiester bonds, and the very recent observation that the region surrounding the peptidyl transferase center of a bacterial
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Its function was to cleave a phosphodiester bond at the start of the mature tRNA nucleotide sequence, thereby releasing the upstream extra or "precursor" nucleotides.
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At that time, it had only been demonstrated that RNA could cleave or ligate phosphodiester bonds.
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"In the prebiotic scenario what causes the nucleotides to start linking via phosphodiester bonds?"
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In the prebiotic scenario what causes the nucleotides to start linking via phosphodiester bonds?
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The sugar molecules are joined together by phosphate groups that form phosphodiester bonds between the third and fifth carbon atoms in the sugar rings.
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Nucleases cut DNA strands by catalyzing the phosphodiester bonds (nucleases that hydrolyse nucleotides from the ends of DNA strands are called endonucleases cut within strands).
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In comparison, the Max homodimer: E-box structure shows that residues in the HLH contact the DNA; Lys57 (Loop) and Arg60 (Helix 2) make nonspecific Coulombic contacts to the phosphodiester backbone
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A possible reason that the Arnt-C / EBP derivatives, in which the HLH has been removed entirely, showed no ability to target the E-box is that the HLH domain of Arnt may interact with the DNA phosphodiester backbone.
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We are creating the world's most trusted encyclopedia and knowledge base. log in, you'll be able to edit this page instantly! enzymes that catalyze the hydrolysis of one of the two ester bonds in a phosphodiester compound. "
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