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phosphoinositides

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Plural form of phosphoinositide.

Etymologies

Sorry, no etymologies found.

Examples

  • Codazzi F, Teruel M, Meyer T (2000) Spatial sensing in fibroblasts mediated by 3′ phosphoinositides.

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  • However, biochemical characterisation of those from Listeria monocytogenes and Leishmania major, demonstrated that, like MptpB, they have phosphatase activity towards phosphoinositides.

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  • Furthermore, we provide experimental evidence that the number of basic residues in the P-loop is critical in determining activity towards poly-phosphoinositides.

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  • In their GTP-bound, active state, ROPs interact with downstream effector proteins to regulate organization of actin and microtubules (MT), vesicle trafficking, production of phosphoinositides, and gradients of reactive oxygen species (ROS) and Ca

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  • We provide examples of the dynamic oligomerization of GFP-tagged myotubularin (MTM1) phosphoinositides phosphatase induced by osmotic stress, and of the ultrastructure of membrane tubules dependent on amphiphysin 2 (BIN1) expression.

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  • It is certainly not excluded that the αK targeting sequence may be targeted to bind to specific phosphoinositides as suggested recently Not only Irgm1, but all mouse IRGM proteins have a membrane-targeting signal in the position of the αK helix in the Irga6 crystal structure.

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  • While the present paper was under review a report appeared concluding that the αK targeting sequence of Irgm1 is specific for the two phosphoinositides PI (3,4) 2P and PI (3,4,5) 3P formed at the mycobacterial phagosome during pathogen uptake

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  • Upon stimulation, PKB PH-domain interaction with phosphoinositides and its concomitant change in conformation allowed the separation of the PH and kinase domains and the associated co-recruited PDK1 to phosphorylate Thr 308.

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  • Komander D, Fairservice A, Deak M, Kular GS, Prescott AR, et al. (2004) Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates.

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  • Zschornig O, Ohki S, Arnold K (2003) Fusion, leakage and surface hydrophobicity of vesicles containing phosphoinositides: influence of steric and electrostatic effects.

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