Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry, genetics A site (on a protein etc) responsible for, or associated with, phosphorylation

Etymologies

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Examples

  • Given that the substrate specificity of a kinase is usually determined by a few key amino-acids surrounding the target phosphosite it is easy to image how kinase-substrate interactions can be easily created and destroyed with few mutations.

    Comparative analysis of phosphoproteins in yeast species Pedro Beltrao 2009

  • Given that the substrate specificity of a kinase is usually determined by a few key amino-acids surrounding the target phosphosite it is easy to image how kinase-substrate interactions can be easily created and destroyed with few mutations.

    Archive 2009-06-01 Pedro Beltrao 2009

  • The height of the flanking bars indicates conservation within the 11 amino acid region surrounding the phosphosite (grey, 88. 2%).

    PLoS Biology: New Articles Marcel A. T. M. van Vugt et al. 2010

  • Interestingly, mapping our phosphorylation sites along with all those from phospho-proteomic databases including PhosphoSitePlus (www. phosphosite.org; [12]) reveals that phosphorylation sites within raptor cluster to two regions located between the HEAT repeat region and the WD-repeat containing C-terminal of raptor (

    PLoS ONE Alerts: New Articles Dana M. Gwinn et al. 2010

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