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- n. A salt or ester of phosphotungstic acid.
Sorry, no etymologies found.
We intracerebrally inoculated hamsters with brain homogenates and phosphotungstate concentrated preparations from CWD positive hunter-harvested (Wisconsin CWD endemic area) and experimentally infected deer of known Prnp genotypes.
We assessed the presence and characteristics of protease-resistant prion protein (PrP res) in brain and 23 other organs and tissues using immunoblots performed directly on total homogenate or following sodium phosphotungstate precipitation to increase PrP res detectability.
Skin PrP res is better detectable along with the kidney PrP res after sodium phosphotungstate (NaPTA) precipitation of PrP res (Lanes 4 and 5), especially after long exposure (Lanes 4L and 5L) (kidney TH loaded in double amount; probed with mAb 3F4).
In an extensive autopsy examination, sodium phosphotungstate (NaPTA) precipitation, a highly sensitive method of PrP A whole body autopsy was performed within 20 hours from death.
After digestion, PrPSc was precipitated by sodium phosphotungstate (PTA).