Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Plural form of piRNA.

Etymologies

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Examples

  • Bartel's group teamed up with researchers at the University of California, Berkeley, and the University of Queensland to identify microRNAs-and similar gene-regulators known as piRNAs (piwi-interacting RNAs) - in a simple sponge and a sea anemone.

    Emaxhealth

  • Finally, we identified two types of germline-specific piRNAs in testis, mapping either to transposons or in strand-specific clusters.

    BioMed Central - Latest articles

  • Lin himself is an internationally re­nowned expert on effects of a large class of small RNAs known as piRNAs.

    Media Newswire

  • The Hannon team has analyzed eight such mutants, showing how the genes disrupted in each mutant impact the piRNA pathway and how it alters the type and number of piRNAs that cells are able to generate.

    PhysOrg.com - latest science and technology news stories

  • Somatic cells are defended by the flamenco piRNA cluster piRNAs arise from so-called 'transposon graveyards' in the genome, where transposon remnants that can no longer jump are clustered.

    PhysOrg.com - latest science and technology news stories

  • In somatic cells, however, the scientists found that the piRNAs utilized by the sole Piwi protein arise from a single cluster called flamenco.

    PhysOrg.com - latest science and technology news stories

  • Hannon's lab had previously found that piRNAs generated from most clusters get amplified in number via a "ping-pong" mechanism - reciprocal cycles of cleavage of RNA molecules by pairs of Piwi-family proteins.

    PhysOrg.com - latest science and technology news stories

  • The cell's counter-response is a form of defense called RNA interference, in which piRNAs partner with members of the Piwi protein family - called Argonaute3 (AGO3), Aubergine (Aub) and Piwi - to "silence" transposons.

    PhysOrg.com - latest science and technology news stories

  • This system is operated by an army of small RNA molecules called Piwi-interacting RNAs (piRNAs) and a set of proteins belonging to the Piwi family.

    PhysOrg.com - latest science and technology news stories

  • By comparing piRNAs in embryos to those in the ovary, then, the CSHL team discovered that while germ cells contained piRNAs targeted to a variety of transposons, the somatic piRNA fraction utilizes only the Piwi protein to selectively suppress gypsy transposons.

    PhysOrg.com - latest science and technology news stories

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