Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A transposon used in genetic engineering

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

From piggyback and an abbreviated form of baculovirus?

Examples

  • Having harvested the skin cells, the scientists reprogrammed them back into stem cells and then used a type of "molecular scissor" technique known as a zinc finger nuclease to snip the cells' genome at precisely the right place and insert a correct version of the gene using a DNA transporter called piggyBac.

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  • He is working with a jumping gene called piggyBac, discovered in a moth.

    Starbulletin Headlines

  • Nagy developed a method that delivers reprogramming genes with a mobile genetic element called piggyBac, which can be popped out of a cell's genome when its work is done.

    The Appleton Post-Crescent Latest Headlines

  • The version used is dubbed "piggyBac" and has been used by researchers to genetically modify a range of organisms.

    ABC News: ABCNews

  • In this case, the researchers used a transposon called "piggyBac" to carry four genes that can transform mouse and human embryonic skin cells into iPS cells.

    ProLifeBlogs

  • The leftover piggyBac sequences were then removed from the cells, cleaning them up and allowing them to be converted into liver cells without any trace of residual DNA damage at the site of the genetic correction.

    The Globe and Mail - Home RSS feed

  • Transposons are promising systems for somatic gene integration because they can not only integrate exogenous genes efficiently, but also be delivered to a variety of organs using a range of transfection methods. piggyBac (PB) transposon has a high transposability in mammalian cells in vitro, and has been used for genetic and preclinical studies.

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  • As an alternative to integrating viral vectors, the piggyBac

    BioMed Central - Latest articles

  • ESC: embryonic stem cell; HIPSC: human induced pluripotent stem cell; IPSC: induced pluripotent stem cell; IRES: internal ribosome entry site; LTR: long terminal repeat; PB: piggyBac; P-HIPSC: protein human induced pluripotent stem cell; STEMCCA: Stem Cell

    BioMed Central - Latest articles

  • "After a lot of trial and error, we came up with a technique of insertion that destroys the piggyBac gene left behind, so even though it gets inserted, it can't do any damage."

    Starbulletin Headlines

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