piperaquine

The combination drug -- comprising arterolane maleate and piperaquine phosphate -- is currently in late-stage trials.

Ranbaxy Transfers New Drug Research Operations 2010

In the 2010 second edition of WHO's guidelines for the treatment of malaria, the relatively new fixed dose combination dihydroartemisinin-piperaquine is included as one of the recommended artemisinin combination therapies.

BioMed Central - Latest articles Frans Herwig Jansen 2010

WHO has now added a fifth ACT - dihydroartemisinin plus piperaquine - to the previous list of recommended medicines.

WebWire | Recent Headlines 2010

Samples were genotyped using both gel and capillary electrophoresis from randomized trials of artemether-lumefantrine (AL) vs. dihydroartemisinin-piperaquine (DP) performed in two areas of Uganda: Kanungu, where transmission is moderate, and Apac, where transmission is very high.

BioMed Central - Latest articles Vinay Gupta 2010

A recent study in Senegal suggests that seasonal IPTc with SP plus piperaquine is highly effective and well tolerated

PLoS ONE Alerts: New Articles Lesong Conteh et al. 2010

In addition to combating resistance to traditional and newer drugs, such as chloroquine and piperaquine, respectively, the new compound can kill the parasite on its own.

Chemical & Engineering News: Latest News 2009

Vietnamese study subjects, however, allowed scientists to estimate that the levels of piperaquine that remain in the body are too low to be effective, and this increases the risk that the malaria parasite will develop resistance.

THE MEDICAL NEWS 2009

Another anti-malarial drug, piperaquine, may be a suitable partner for artemisinin in the treatment of malaria.

THE MEDICAL NEWS 2009

Net that the team's 2-in-1 drug, "not only adds a new [type of drug] to the list of antimalarials, but also provides a uniquely powerful therapeutic tool to enhance the efficacy of newer drugs (e.g. piperaquine) and to restore the efficacy of older drugs (e.g. quinine and chloroquine)".

SciDev.Net 2009

The results of two new large scale trials show that the combination of dihydroartemisinin and piperaquine (DHA+PQP) not only is effective against uncomplicated malaria in a way which is comparable to other artemisinin-based combination therapies (ACTs), but it also protects patients against new infections for at least two months after treatment.

Emaxhealth 2009