from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. The influence of a single gene on multiple phenotypic traits; pleiotropism
  • n. The existence of drug effects other than the one for which the drug was designed; usually implies additional beneficial effects.


Sorry, no etymologies found.


  • The Modern Synthesis replaced "one gene – one trait" with "one gene – one enzyme", then added polygenesis and pleiotropy.


  • Do you think that no real scientist has ever considered the effects of pleiotropy and epistasis?

    It's more than genes, it's networks and systems - The Panda's Thumb

  • Professor Flegr has mentioned also pleiotropy and epistatic interactions mentioned in PZMyers article using layman words.

    It's more than genes, it's networks and systems - The Panda's Thumb

  • They recognize a widespread phenomenon called ‘pleiotropy’, whereby genes have more than one effect, seemingly unconnected.


  • In the real world genes often affect more than one trait (pleiotropy), or more than one gene affects a given trait (polygeny).

    Death of a popular anti-ID argument

  • A similar phenomenon can occur at the phenotypic level through a genetic property known as pleiotropy.


  • I suspect some kind of antagonistic pleiotropy may be at work.

    Archive 2008-04-01

  • For $35 an hour, I obliged and watered down the material, removing all “advanced” content points, such as co-dominance and pleiotropy though these were subjects that I covered in the basic biology classes I taught a couple of years earlier.

    Archive 2008-08-01

  • Limitations and complications of the theory include changes in environment or genetic background, enzymes with sharply defined optima of activity, overdominance, pleiotropy, multifunctional enzymes and branched metabolic pathways.

    Darwin and neutrality - The Panda's Thumb

  • "I came across this concept of antagonistic pleiotropy that certain genes can actually have opposite effects across the lifespan," he said.

    Latest News - Yahoo!7 News


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