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- noun Plural form of
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Coatings that spear bacteria - using amphipatic polycations and antimicrobial peptides - tend to clog, also losing effectiveness.
A distinctive effect of protamine (which might be shared with polylysines and histones but not with non-peptidic polycations) is the activation of RyR2 in the presence of nanomolar cytosolic Ca
This is more similar to rectification of channel conductance induced by other polycations than to the action of selective conductance modifiers (ryanoids, imperatoxin).