Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun The presence of several polyps in the body.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun medicine A hereditary disease characterised by numerous polyps that erupt in various parts of the body, especially the colon

Etymologies

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Examples

  • Because Familial adenomatous polyposis is hereditary, the risk of developing the features associated with FAP can be passed from generation to generation in a family.

    Familial Adenomatous Polyposis

  • Individuals with familial adenomatous polyposis are also at increased risk to develop benign and malignant tumors outside of the gastrointestinal tract.

    Familial Adenomatous Polyposis

  • It is important to note that patients with familial adenomatous polyposis are at increased risk to develop other types of cancer in addition to cancer of the colon or stomach.

    Familial Adenomatous Polyposis

  • Approximately 75 percentto 80 percentof patients with familial adenomatous polyposis inherit an altered copy of the APC gene from a parent who also has FAP.

    Familial Adenomatous Polyposis

  • It is caused by alterations in the adenomatous polyposis coli (APC) gene.

    Familial Adenomatous Polyposis

  • If a mutationin either BMPR1A or SMAD4 is identified, the genetic counselor can next examine whether the alteration has been previously reported in other individuals with juvenile polyposis syndrome (JPS).

    Juvenile Polyposis

  • How is juvenile polyposis syndrome (JPS) inherited?

    Juvenile Polyposis

  • Additional sources of information for familial adenomatous polyposis (FAP)

    Familial Adenomatous Polyposis

  • In patients with juvenile polyposis syndrome, however, each cell contains only one working copy of either BMPR1A or SMAD4.

    Juvenile Polyposis

  • Colorectal cancer is the most common cancer seen in individuals with juvenile polyposis syndrome (JPS), but cancers in other parts of the digestive system have also been described, such as cancers of the stomach, upper gastrointestinal tract and pancreas.

    Juvenile Polyposis

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