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from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A sequence of several proline residues in a polypeptide or protein; tends to generate an anomalous left-handed helix conformation


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  • Here we examine the role of the SH3 domain of postsynaptic density 95 (PSD95) by using mice that carry a single amino-acid substitution in the polyproline-binding site.

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  • Inexplicably broad distributions also have been observed in smFRET measurements on polyproline helices

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