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- adjective Of or pertaining to a
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Microarray analysis of total and polysomal RNAs nonetheless identified distinct sets of mRNAs regulated either positively or negatively by eIF3e; functional classification of these revealed a marked enrichment of genes involved in cell proliferation, invasion and apoptosis.
Total and polysomal-bound mRNA populations purified from immature, 4h and 16h LPS-stimulated human monocyte-derived DCs were analyzed on Affymetrix microarrays U133 2.0.
We are currently combining polysomal profiling and microarrays to investigate translationally regulated genes relevant for longevity.
Hypothetical gemin5 mRNPs would likely exist in translationally-silent, sub-polysomal complexes through preclusion of eIF4E association with the cap.