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Examples
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Although an invigorating piece of chemistry, what is missing from their demonstration is what is missing from Powner's and that is any clear indication of pre-biotic plausibility.
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If the steps leading to the appearance of the pyridimines in a pre-biotic environment are not yet plausible, then neither is the appearance of a self-replicating form of RNA.
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You, as other RNA - world proponents, fail to mention that all the prebiotic experiments are carried out with purefied chemicals, in very carefully sequenced reactions … something that never would have happened in pre-biotic conditions.
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And what does biology have to do with the pre-biotic environment?
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Do we see a continuous chain of natural causes which go from apes to small furry mammals to reptiles to slugs to slime molds to blue green algae, and finally all the way back to a pre-biotic soup, with no event in the chain ever signaling the activity of an intelligent agent?
Blast From the Past 2010
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Nevertheless, in his recent review on the Biologos website, Prof. Darrel Falk characterizes me as merely a well-meaning, but ultimately unqualified, philosopher and religious believer who lacks the scientific expertise to evaluate origin-of-life research and who, in any case, has overlooked the promise of recent pre-biotic simulation experiments.
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Building a house of cards through the action of wind and shaking have more chances of success than assembling a computer spontaneously from random molecules in a pre-biotic soup.
Another Look 2009
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The question was not directly related to the plausibility of Adenine in a pre-biotic soup (however it may be indirectly related).
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The scientific press justifiably heralded this as a breakthrough in pre-biotic chemistry because previously chemists had thought (as I noted in my book) that the conditions under which ribose and bases could be synthesized were starkly incompatible with each other.
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If experiments conducted in the here and now are to shed light on the there and then, they must meet two conditions: They must demonstrate in the first place the existence of a detailed chemical pathway between RNA precursors and a form of self-replicating RNA; and they must provide in the second place a demonstration that the spontaneous appearance of this pathway is plausible under pre-biotic conditions.
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