from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. An early symptom indicating the onset of an attack or a disease.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. an early symptom warning of the onset of a disease

from the GNU version of the Collaborative International Dictionary of English

  • n. A forerunner; a precursor.
  • n. A premonitory symptom; a symptom or sensation experienced by a person which presages the onset of a disease or abnormal physiological event.

from The Century Dictionary and Cyclopedia

  • n. A forerunner.
  • n. Any prodromal symptom.
  • n. A precursory or preliminary treatise; a prodromus (which see).

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. an early symptom that a disease is developing or that an attack is about to occur


from The American Heritage® Dictionary of the English Language, 4th Edition

French, from Latin prodromus, precursor, from Greek prodromos, precursor : pro-, forward; see pro-2 + dromos, running.

from Wiktionary, Creative Commons Attribution/Share-Alike License

Probably by analogy with syndrome (pro- + -drome), but consistent with Ancient Greek προδρομή (prodromē, "running forward, sally, skirmish")


  • This schizophrenia "prodrome" - the early signs - involves a troubled mental state usually found in teens and young adults.


  • We and others have found that IFN-gamma and other pro-inflammatory cytokines interact with processing and production of the pathological hallmark feature of Alzheimer's disease (AD); A-beta peptide; suggesting that inflammaging may be a "prodrome" to AD.

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  • The news is that a constellation or "prodrome" of possible, impending serious illness has been long-recognized, and that now hopes are rising that they might trigger effective, early intervention.

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  • The Four Phases of a Migraine 1 Premonitory, or prodrome.

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  • Psychosis risk is the putative prodrome of schizophrenia, minor neurocognitive is the prelude of dementia,and mixed anxiety/depression presages more clearly defined mood and anxiety disorders.

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  • I was aware that an aura was a prodrome of a migraine.

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  • I did learn a few new things, like the SAT word “prodrome,” which meant “a warning sign of an oncoming headache.”

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  • Even patients who presented with ADAMTS13 levels below 10% were heterogeneous, initially presenting in multiple clinical categories (HSCT, postpartum, bloody diarrhea prodrome, additional or alternative disorders, as well as idiopathic).

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  • In machine and knitting and books of overall intro machine each prodrome must introduce structured with a worthy plant of oil.


  • The prodrome started with a feeling like someone was repeatedly stabbing the roof of my mouth and lower lip with a needle.

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