Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun Any of various drugs that are administered in an inactive form and converted into active form by normal metabolic processes.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun pharmacology A
drug that isadministered in aninactive form that ismetabolised in the body into a biologicallyactive compound.
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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It belongs to the class of drugs called prodrug - an inactive compound that is converted into an active drug by the body's metabolic processes.
Medindia Health News 2009
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It belongs to the class of drugs called prodrug - an inactive compound that is converted into an active drug by the body's metabolic processes.
Medindia Health News 2009
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Like many cancer drugs, sunitinib is a "prodrug" that requires the CYP450 family of enzymes in the liver to activate the drug for it to be effective.
PhysOrg.com - latest science and technology news stories 2010
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Nektar is developing NKTR-102, a novel prodrug which is a PEGylated form of irinotecan.
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Nektar is developing NKTR-102, a novel prodrug which is a PEGylated form of irinotecan.
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Nektar is developing NKTR-102, a novel prodrug which is a PEGylated form of irinotecan.
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Nektar is developing NKTR-102, a novel prodrug which is a PEGylated form of irinotecan.
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The company also has other advanced drug delivery technologies including Cobalamin (TM) - mediated targeted delivery and oral drug delivery, its proprietary nanopolymer delivery technology based on the natural vitamin B12 uptake mechanism; Angiolix (R), a humanized monoclonal antibody which acts as an anti-angiogenesis factor and is targeted to breast cancer; Prodrax (R), a non-toxic prodrug which is activated in the hypoxic zones of solid tumors to kill cancer cells;
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The company also has other advanced drug delivery technologies including Cobalamin-mediated targeted delivery and oral drug delivery, its proprietary nanopolymer delivery technology based on the natural vitamin B12 uptake mechanism; Angiolix, a humanized monoclonal antibody which acts as an anti-angiogenesis factor and is targeted to breast cancer; Prodrax, a non-toxic prodrug which is activated in the hypoxic zones of solid tumors to kill cancer cells; Alchemix, a chemotherapeutic agent that combines multiple modes of action to overcome drug resistance.
Nano Tech Wire 2009
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Because fosphenytoin is a prodrug and is converted to phenytoin after administration, any concern regarding this association is also applicable to fosphenytoin.
Caution for Asians on epilepsy drug GreenFertility 2009
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