Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. The first stage of mitosis, during which the chromosomes condense and become visible, the nuclear membrane breaks down, and the spindle apparatus forms at opposite poles of the cell.
  • n. The first stage of meiosis, constituted by a series of events that include the thickening and coiling of the chromosomes, synapsis of homologous chromosomes, tetrad formation, and crossing over.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. the first stage of mitosis, during which chromatin condenses to form the chromosomes
  • n. the first stage of meiosis

from The Century Dictionary and Cyclopedia

  • n. In cytology, a preparatory stage in mitotic cell-division. The prophase is characterized by a more intense staining of the chromatin, the resolution of the reticulum into a skein or spireme, the breaking up of the latter into chromosomes, the appearance of the achromatic spindle, and the disappearance of the nuclear wall. The prophase is succeeded by the metaphase.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. the first stage of mitosis
  • n. the first stage of meiosis

Etymologies

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Examples

  • Prophase - The first stage of mitosis is known as prophase, where the nuclear chromatin starts to become organized and condenses into thick strands that eventually become chromosomes observable in the optical microscope (Figure 1 (b)).

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  • Diagrams of late prophase chromosomes (1000-band stage) of human, chimpanzee, gorilla, and orangutan (left to right for each number).

    Dog Bites Man - The Panda's Thumb

  • This is before the nucleolus breaks up, which it does at a later stage in the first meiotic prophase.

    Nobel Lecture The Significance of Responses of the Genome to Challenge

  • A crossover at the meiotic prophase, as shown in Fig. 2, produces a dicentric chromosome that simulates two normal chromosomes attached together at the ends of their short arms, and a fragement chromosome with telomeres at both ends.

    Nobel Lecture The Significance of Responses of the Genome to Challenge

  • Its "epigenesis" is shown to be a literary example of the phases of cell division, with discussions of its prophase, metaphase, anaphase, and telophase.

    The Dream of Mind and Machine

  • Even in the middle of the twentieth century, textbooks and teachers could still be found perpetuating this error, in spite of the fact that a careful look at Flemming's own figures of nuclei in early prophase shows quite clearly that more than two chromosome ends are apparent in various prophase nuclei!

    GENETIC CONTINUITY

  • This conception, which was based simply on inadequate observations of the number of free chromosome ends in the early prophase nuclei, was less in conflict with any of the principles of genet - ics, and had a much longer life.

    GENETIC CONTINUITY

  • I to III, prophase; IV, metaphase; V and VI, anaphase; VII and VIII, telophase.

    Illustrations. Fig. 2

  • • These factors prevent primary oocytes from maturing beyond the prophase of the 1st meiotic division.

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  • • The primary oocytes remain in prophase and do not complete their 1st meiotic division until they begin to mature and are ready to ovulate.

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